regulate vascular pathological condition

This non-invasive, safe and easy-to-use method allow us determining blood volume and its components (e.g. 1C), combined with bioelectrical impedance analysis. In this context, we measure blood volume using the carbon monoxide rebreathing method (Fig. 1D) – to study its role in physiological and pathological conditions.įurther, blood volume regulation is to a big extent regulated by the vasculature. In our lab we are able to assess sympathetic nervous activation directly in the peroneus nerve by microneurography (Fig. Sympathetic activation is crucial for regulation vascular tone. Further, pulse wave analysis (PWA), as a measure of arterial stiffness, and the sonographic assessment of the intima-media thickness of the carotid arteries help to assess the vasculature structurally.

We now have a huge armamentarium to study endothelial function in several ways to assess cardiovascular risk, early atherosclerosis and to estimate prognosis. With the “retinal vessel analyzer, Figure 1B” we are able to non-invasively and accurately study vascular function in the retinal arterioles and veins via flicker-light induced endothelial dependent vasodilation and neurovascular coupling. flow mediated dilatation – FMD, Figure 1A) we established – with the support of the SNSF and other competitive grants – a novel technique for the measurement of endothelial function in our lab. Beside the established methods to invasively- and non-invasively measure endothelial function (e.g.

Regulate vascular pathological condition